The 2022 Vuelta a Andalucía Ruta del Sol (English: Tour of Andalucia Route of the Sun) was a road cycling stage race that took place between 16 and 20 February 2022 in the autonomous community of Andalusia in southern Spain.

[1] The race was rated as a category 2.Pro event on the 2022 UCI ProSeries calendar, and was the 68th edition of the Vuelta a Andalucía.

[2] After the 2021 edition was postponed to May due to the COVID-19 pandemic in Spain,[3][4] the race returned to its traditional mid-February timeslot.

In total, 140 riders started the race, of which 108 finished.

[9] Before stage 3, Gazprom–RusVelo and Human Powered Health both withdrew from the race after returning multiple positive COVID-19 test results.