The 2022 Massachusetts State Collegiate Athletic Conference football season was the 10th season of the Massachusetts State Collegiate Athletic Conference football taking place during the 2022 NCAA Division III football season.
The MASCAC Championship Game was played at Panther Field in Plymouth, New Hampshire, on November 12, 2022.
The game featured the UMass Dartmouth Corsairs and the Plymouth State Panthers.
Updated with the results of all regular season conference games.
The following individuals received postseason honors as voted by the Massachusetts State Collegiate Athletic Conference football coaches at the end of the season.