Peter Wright was the defending champion after defeating Dimitri Van den Bergh 18–9 in the 2021 final.

[1] However, he was defeated by Van den Bergh 16–14 in the quarter-finals, in a rematch of the previous year's final.

Michael van Gerwen won his third World Matchplay title, defeating Gerwyn Price 18–14 in the final.

[2][3] Gerwyn Price hit the first nine-dart finish in the tournament for four years in his semi-final win over Danny Noppert.

[6] The top 16 players on the PDC Order of Merit at the cut-off point on 11 July were seeded for the tournament.