[21][22] On 26 July, Arsenal played their third and final game of the 10-day USA tour against La Liga side Barcelona at SoFi Stadium, the home of the National Football League's Los Angeles Rams which is also owned by Kroenke Sports and Entertainment.

[44] Arsenal announced on 15 July that 24-year-old English midfielder Declan Rice, who was born and raised in London, had joined the club from Premier League side West Ham United on a long-term contract,[45][46] and would wear the number 41 shirt.

On 3 August, the Gunners confirmed that American defender Auston Trusty had joined Premier League side Sheffield United on a permanent deal for a reported fee of £5 million.

[49][50] Six days later, the club announced that American goalkeeper Matt Turner had joined Premier League side Nottingham Forest on a permanent transfer for a fee reported to be £10 million.

[53] Arsenal confirmed on 15 August that the club had signed 27-year-old Spanish goalkeeper David Raya on a season-long loan from Premier League side Brentford with the option to make the move permanent in summer 2024.

Tomiyasu was controversially sent off by referee David Coote on 67 minutes for two quick bookable offences – the first yellow was for delaying a throw-in, and the second was harshly awarded for a minor foul on Palace's Jordan Ayew in midfield.

Gabriel Jesus recovered from his knee injury to be named in a matchday squad for the first time; and Saka made his 83rd consecutive Premier League appearance for the Gunners, breaking the club record in the competition set by Paul Merson between 1995 and 1997.

[86] Five minutes later, Vieira sprung forward on the counter, fed Gabriel Jesus and the Brazilian ran through on goal, cut away from a sliding Diogo Dalot and slotted the ball past goalkeeper André Onana, sealing a 3–1 victory.

[89] Sixteen Arsenal first-team players (excluding players who were loaned out) were named in their respective countries' senior squads for international fixtures in September: Trossard (Belgium), Gabriel Jesus, Gabriel Magalhães and Martinelli (Brazil), Nketiah, Ramsdale, Rice and Saka (England), Karl Hein (Estonia), Saliba (France), Havertz (Germany), Tomiyasu (Japan), Ødegaard (as Norway's captain), Jakub Kiwior (Poland), Raya (Spain), and Oleksandr Zinchenko (Ukraine).

[110] Arsenal suffered their first defeat of the season with a 2–1 loss to Ligue 1 side Lens at Stade Bollaert-Delelis in the Champions League on Tuesday, 3 October, after being late arriving to northern France on Monday night with their flight delayed by around five hours due to bad weather.

Arteta's side doubled their advantage in the 53rd minute, as Rice intercepted the clearance and drove forward before passing to Gabriel Jesus, who cut inside and curled a shot into the top right corner from a narrow angle, becoming the second player to score in his first three Champions League games for Arsenal, after Marouane Chamakh in 2010.

[140][141] Sixteen Arsenal first-team players (excluding players who were loaned out) joined up with their respective senior national teams for international fixtures in November: Trossard (Belgium), Gabriel Jesus, Gabriel Magalhães and Martinelli (Brazil), Elneny (Egypt), Ramsdale, Rice and Saka (England), Hein (Estonia), Saliba (France), Havertz (Germany), Jorginho (Italy), Tomiyasu (Japan), Kiwior (Poland), Raya (Spain), and Zinchenko (Ukraine).

Havertz tucked home from close range on 13 minutes,[147] becoming the 100th different Arsenal player to score a goal for the Gunners at Emirates Stadium since the club moved from Highbury in 2006.

[149] In the 21st minute, Gabriel Jesus collected a Saka pass and slotted the ball past visiting goalkeeper,[147] becoming the first player to score in each of his first four Champions League appearances for an English side.

[155][158][159] Having missed a slide tackle on White in the 45th minute, Newcastle midfielder Bruno Guimarães challenged Jorginho from behind and elbowed the latter in the back of the head after the ball had gone, leaving the Italian crocked on the ground.

Saka's opener in the 6th minute was the Gunners' 100th goal of 2023, making Arsenal the fifth big five European league team to reach this total across all competitions in 2023, after Manchester City, Real Madrid, Bayern Munich and Bayer Leverkusen.

The Gunners had a penalty shout in the 47th minute when Villa's Douglas Luiz caught Gabriel Jesus' ankle inside the box, but VAR quickly decided not to overturn a no-penalty decision.

[180] An off-the-ball incident occurred in the 87th minute as Nketiah attempted to run in behind Villa defender Diego Carlos, the Arsenal striker was elbowed in the face by the Brazilian, and fell to the ground.

[180] With top spot already assured, Arsenal made the trip to the Netherlands on 12 December for the final Champions League group match against Eredivisie side PSV Eindhoven.

The Gunners found the breakthrough on 53 minutes when Saka's corner was inadvertently flicked on by Brighton defender Jan Paul van Hecke for an unmarked Gabriel Jesus to head in at the far post.

Arsenal's third goal came in the 59th minute, as Raya claimed a cross following a Palace corner and his 40-yard throw sent Gabriel Jesus on his way; the Brazilian then swept the ball across to Trossard, who beaten the last defender before rifling beyond Henderson.

[207] On English transfer deadline day, 1 February, Arsenal confirmed that Icelandic goalkeeper Rúnar Alex Rúnarsson had been recalled from his loan at Championship side Cardiff City and would depart the club following the termination of his contract.

[211] The hosts dominated the first 45 minutes, but Liverpool were level just before half-time without having had a shot on target, as Saliba's indecisiveness allowed Luis Díaz to pass across goal, with the ball inadvertently hitting Gabriel Magalhães before rolling into the net.

Neither team was able to break the deadlock until the fourth and final minute of second-half stoppage time, when Martinelli tried to smash a long diagonal to Saka but the ball went straight to Porto defender Otávio, who passed to Galeno, whose long-range curling shot found the back of the net.

The English goalkeeper dawdled on a routine backpass in his six-yard box under little pressure and took too long on a clearance, which allowed Brentford forward Yoane Wissa to close down and block it into the net.

[242] The result ended Arsenal's eight-match losing streak in all competitions at the Etihad,[243] making Arteta the first manager to go unbeaten against both Jürgen Klopp and Pep Guardiola in a Premier League season.

Saka gave Arsenal an early advantage; but the six-time European champions drew level thanks to former Gunner Serge Gnabry, and then went ahead through a Harry Kane penalty.

The hosts pulled two back in the second half, as Cristian Romero punished Raya's error and Son Heung-min scored from the spot after Rice fouled Ben Davies.

Timber made his first-team return as a 69th-minute replacement for White, marking a seven-month wait for his second Premier League appearance after his ACL injury on the opening day of the season.

[518] On 12 May, Arsenal announced their third and final pre-season fixture in the US this summer, against Barcelona at SoFi Stadium, the home to the National Football League's Los Angeles Rams which is also owned by Kroenke Sports and Entertainment.