The 2023 Cary Challenger II was a professional tennis tournament being played on hard courts.

It was the 11th edition of the tournament which was part of the 2023 ATP Challenger Tour.

It took place in Cary, North Carolina, United States between 11 and 17 September 2023.

The following players received wildcards into the singles main draw: The following players received entry into the singles main draw using protected rankings: The following players received entry from the qualifying draw: The following player received entry as a lucky loser: