The 2023 Strade Bianche Donne was an Italian road cycling one-day race that took place on 4 March 2023.

It was the ninth edition of Strade Bianche Donne and the fifth event of the 2023 UCI Women's World Tour.

The race was won by Dutch rider Demi Vollering, who outsprinted her SD Worx teammate Lotte Kopecky in Siena.

[2] The final kilometre in Siena to the finish line in the Piazza del Campo has a maximum gradient of 16%.

[4] Amanda Spratt of Trek–Segafredo retained the leaders jersey of the UCI Women's World Tour.