It was the team's first season without head coach Jay Mims, after the club announced his resignation on December 16.

[1] He was replaced by Dominic Casciato, who was most recently an assistant coach at El Paso Locomotive of the USL Championship.

[2] Union Omaha played their home games at Werner Park, located in Papillion, Nebraska, United States.

Union Omaha announced their initial list of returning players on December 7, 2022.

[20] Source: USL League One[22] Numbers after plus–sign (+) denote appearances as a substitute.