The 2024–25 CAF Champions League group stage began on 26 November 2024 and ended on 19 January 2025.
The draw for the group stage was held on 7 October 2024, 11:00 GMT (14:00 local time, UTC+3), in Cairo, Egypt.
The teams were seeded by their performances in the CAF competitions for the previous five seasons (CAF 5-year ranking points shown next to every team).
The winners and runners-up of each group advanced to the quarter-finals of the knockout stage.
If tied on points, tiebreakers were applied in the following order (Regulations III.