The 2024 Antofagasta Challenger was a professional tennis tournament played on clay courts.

It was the second edition of the tournament which was part of the 2024 ATP Challenger Tour.

It took place in Antofagasta, Chile between 23 and 29 September 2024.

1 Rankings are as of 16 September 2024.

[1] The following players received wildcards into the singles main draw: The following players received entry into the singles main draw as alternates: The following players received entry from the qualifying draw: The following players received entry as lucky losers: