The Patriots played their home games at Spuhler Field as a member of the Atlantic 10 Conference.

George Mason was entering the season as the defending Atlantic 10 Conference baseball tournament champions.

[3] In the 2023 NCAA Division I baseball tournament, George Mason entered the Winston-Salem Regional as the fourth seed, facing off against the third-seeded Northeastern of the CAA, the second-seeded Maryland of the Big Ten, and the top-seeded hosts, Wake Forest of the ACC.

[4] Mason went 2–2 in the tournament, defeating Northeastern and Maryland,[5] but losing twice to Wake Forest.

George Mason was picked to finish second in the conference and received two first-place votes.