The 2025 Southeastern Louisiana Lions football team will represent Southeastern Louisiana University as a member of the Southland Conference during the 2025 NCAA Division I FCS football season.

They will be led by head coach Frank Scelfo, who will be coaching in his eighth season with the program.

The Lions will play their home games at Strawberry Stadium in Hammond, Louisiana.

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Key: POS: Position, SOLO: Solo Tackles, AST: Assisted Tackles, TOT: Total Tackles, TFL: Tackles-for-loss, SACK: Quarterback Sacks, INT: Interceptions, BU: Passes Broken Up, PD: Passes Defended, QBH: Quarterback Hits, FR: Fumbles Recovered, FF: Forced Fumbles, BLK: Kicks or Punts Blocked, SAF: Safeties, TD : Touchdown