Talk show topics include science, current affairs, health, conservation, publishing, gender and queer culture, music, arts and theatre.

This caused friction within the station but 2SER organised a series of highly lucrative fund raising events called Freaky Loops in association with Sydney promoters such as Cryogenesis, Clan Analogue, Club Kooky and Elefant Traks which sustained the move to a new musical format for several years until 2001.

Management addressed the situation by reducing the number of paid staff, putting forward proposals to scale down the use of its studio at Macquarie University and attempting to cater for a slightly older audience.

[9] The station celebrated its 40th anniversary in October 2019 with a podcast series,[10] exhibition[11] and book, An Incomplete History of Community Radio: 2SER's 46 Boxes of Stuff.

[12] The station's long-term publication, Listening Post, was also digitised in full and placed in the Australian open access archive Trove.