Bromopyruvic acid

Bromopyruvic acid is the organic compound with the formula BrCH2COCO2H.

This colorless solid is the brominated derivative of pyruvic acid.

It has been investigated as a metabolic poison and an anticancer agent.

The pyruvate transporter system can be used to deliver bromopyruvate inside trypanosomal cells.

Once intracellular, the primary target of 3BP is glyceraldehyde-3-phosphate dehydrogenase, which is highly sensitive to inhibition by bromopyruvate.

Skeletal formula of bromopyruvic acid
Ball-and-stick model of the bromopyruvic acid molecule