33 South Sixth Street is a 52-story office building located in the heart of Minneapolis's 64-square block skyway system.

Current tenants include Target Corporation, and law firms Meagher & Geer, and Stoel Rives.

Local retailers include Len (casual men's and women's fashion boutique), Pacifier (luxury infant and toddler apparel and toys), along with others.

Sports Authority announced in May 2016 that it would be shuttering all of its US stores, leaving City Center with a large vacancy on the corner of 7th Street and Nicollet Avenue in August 2016.

Rosa Mexicano quietly shuttered its downtown Minneapolis location at Hennepin Avenue and 6th Street in November 2016.