The 3rd Nuclear Power Plant Defense Battalion is a battalion of the National Guard of Ukraine tasked with CBRN defense specifically of the Khmelnytskyi Nuclear Power Plant and has seen action against Russian forces during the Russian invasion of Ukraine.

It was established on 1 July 1992 as a part of the Internal Troops of Ukraine to protect and guard the Khmelnytskyi Nuclear Power Plant.

In 2014, it became a part of the National Guard of Ukraine and started operations during the War in Donbass with its special purpose platoon seeing heavy combat.

It was reported that throughout the Russo-Ukrainian war, at least four personnel of the Battalion were killed in action.

[5] Khmelnytskyi Nuclear Power Plant was again attacked on 29 November 2023 with several explosions being reported near it.