The Ministry of Internal Affairs of Ukraine (Ukrainian: Міністерство внутрішніх справ України, romanized: Ministerstvo vnutrishnikh sprav Ukrainy [mʲinʲiˈstɛrstwɔ ˈwnutʲrʲiʃnʲix sprau̯ ʊkrɐˈjine], MVS) is the ministry of the Ukrainian government that oversees the interior affairs of Ukraine.

The ministry carries out state policy for the protection of rights and liberties of citizens, investigates unlawful acts against the interest of society and state, fights crime, provides civil order, ensures civil security and traffic safety, and guarantees the security and protection of important individuals.

This changed in July 2015, in the aftermath of Euromaidan, with the introduction of reforms by Ukrainian president Petro Poroshenko to reduce corruption, whereby the militsiya was replaced with the National Police.

Many former ministers previously had experience with serving in the police, and were, prior to taking up the ministerial post, generals of the militsiya.

Yuriy Lutsenko and Vasyl Tsushko are the only former holders of this office who had never served in any law enforcement agency.