4-Aminoquinoline

4-Aminoquinoline is a form of aminoquinoline with the amino group at the 4-position of the quinoline.

[1] A variety of derivatives of 4-aminoquinoline are antimalarial agents useful in treating erythrocytic plasmodial infections.

[2] Examples include amodiaquine, chloroquine, and hydroxychloroquine.

[3] Other uses for the derivatives are: anti-asthmatic, antibacterial, anti-fungal, anti-malarial, antiviral and anti-inflammatory agents.

[1] A patent application for 4-aminoquinoline compounds was filed in 2002 and published in 2005.

Structural formula of 4-aminoquinoline
Space-filling model of the 4-aminoquinoline molecule