Lt. Col. Samuel W. Ferguson of the 28th Mississippi Cavalry, then recovering at home in Charleston from an injury received when he fell from his horse, was appointed colonel of the regiment.

However, Ferguson's appointment was never confirmed, and he returned to his command in Mississippi without ever joining the regiment.

Col. Robert J. Jeffords took temporary command of the regiment until John Dunovant, previously dismissed as major of the 1st SC Regulars, was appointed colonel in July 1863.

Although officially designated a regiment, the companies remained dispersed at various locations along the South Carolina coast.

This article about a specific military unit of the American Civil War is a stub.