Artillery Regiments were constituted on 8 March 1898, three weeks after the explosion of the USS Maine in Havana, Cuba on 15 February 1898, as the United States' declaration of war on Spain and commencement of the Spanish–American War seemed imminent.

[1][2][3] Colonel Edward B. Williston, a Medal of Honor recipient for actions in the Civil War, was the regiment's first commander.

[1] Constituted 5 August 1942 in the Army of the United States as Headquarters and Headquarters Battery, 6th Antiaircraft Artillery Automatic Weapons Group (or 6th Coast Artillery Group (AA)).

[1] Constituted 8 February 1943 in the Army of the United States as the 778th Coast Artillery Battalion (AA) (Auto-Weapons).

Redesignated 13 October 1948 as the 25th Antiaircraft Artillery Automatic Weapons Battalion and allotted to the Regular Army.