7,12-Dimethylbenz[a]anthracene (DMBA) is an immunosuppressor and a powerful organ-specific laboratory carcinogen.
[2] DMBA is widely used in many research laboratories studying cancer.
DMBA serves as a tumor initiator.
Tumor promotion can be induced with treatments of 12-O-tetradecanoylphorbol-13-acetate (TPA) in some models of two-stage carcinogenesis.
[3] This allows for a greatly accelerated rate of tumor growth, making many cancer studies possible.