After high school he studied for priesthood at the Shadowbrook Jesuit seminary in Lenox, Massachusetts, while also attending Boston College.
He went on to attend the Yale School of Drama for a year and a half before leaving to begin his work in professional theatre.
In that same year, Antoon presented Subject to Fits, a play written by his Yale friend Robert Montgomery, to Joseph Papp, founder of the New York Shakespeare Festival.
[3] Antoon went on to direct numerous original Broadway productions, including The Good Doctor, The Effect of Gamma Rays on Man-in-the-Moon Marigolds, and Sherlock's Last Case.
[9] In 1975, Antoon directed a production of Trelawny of the 'Wells' featuring the Broadway debuts of Meryl Streep and Mandy Patinkin.
[10] In 1984, Antoon directed a production of The Rink with Liza Minnelli and Chita Rivera for which he was nominated for a Drama Desk Award.