Then the road goes via Wilrijk in the direction of Brussels (the traffic coming from Ghent takes the A112 via the Jan De Vos Tunnel).

Then, in Boom, a tunnel leads the A12 under the Rupel river, where the frontage roads take a bridge and then fuse with the motorway itself.

However, in 2010, the intersections are being modernised instead and a frontage road is partially being built in the direction of Brussels.

Between Zandvliet and Stabroek (north of Antwerp), the railway runs on the central reservation.

However, for much of its length it runs a few kilometers to the west of and parallel with the A1 which forms a part of the European route E19.