The A415 is a British A road which runs from the A4074 at Berinsfield, Oxfordshire (51°39′33″N 1°10′34″W / 51.6591°N 1.1762°W / 51.6591; -1.1762 (A415 road (southeastern end))), to Witney (51°47′07″N 1°29′47″W / 51.7852°N 1.4965°W / 51.7852; -1.4965 (A415 road (northwestern end))), passing through Abingdon, Marcham and Kingston Bagpuize.

It crosses the River Thames twice, at Abingdon Bridge and Newbridge.

When UK roads were first classified in 1922, the A415 started at a junction with the A4 just west of Maidenhead in Berkshire.

[1] It ran through Henley-on-Thames and Benson to Shillingford where it joined the then A42.

It left the A42 a mile west at Dorchester.