The A577 is an A road in England which runs from Boothstown, Greater Manchester to Ormskirk, Lancashire.

The A577 starts at A572 in Boothstown, where it climbs uphill and over the A580 and into Tyldesley.

The road heads into Hindley, crossing the A58 and goes into Wigan.

It then goes through Pemberton, past the M6 and the M58 junctions at Orrell.

After going past an urbanized area, it ascends slightly and goes into Westhead.