ADX-71441 is a GABAB receptor positive allosteric modulator currently being investigated as a potential treatment for anxiety, epilepsy, pain and other conditions.

[1] This result was observed in both alcohol dependent and non-dependent animals.

[4] This compound has also been shown to reduce anxiety in people with PTSD.

[5] Experiments have shown that this compound was able to decrease hypersensitivity to pain in mice, Guinea pigs and rats.

[5] ADX-71441 has been shown to have less tolerance and side effects than direct GABAB agonists, such as baclofen.