[2] Independent software vendors (ISV), such as game developers, can use what is called a Wwise audio plugin to offload such computations to the TrueAudio DSPs.

The video games Murdered: Soul Suspect, Star Citizen, Thief and Lichdom: Battlemage (uses CryEngine) can be configured to use AMD TrueAudio if present.

[citation needed] There is an audio plug-in for Audiokinetic's Wwise (Wave Works Interactive Sound Engine) to off-load computation to the TrueAudio DSP(s).

Wwise is available for Linux, OS X, Windows, PlayStation 4, Xbox One et al. GenAudio's AstoundSound, a highly optimized collection of advanced DSP C/C++ software available as a library or a plugin for augmenting real-time audio engines on Linux, OS X, Windows as well as Android and iOS, can make use of AMD TrueAudio.

There is a beta cross-platform support since end of 2019[12] and in 2021 it's still a pull request[13] but now this branch configured as default and compiles on Windows, Linux, and MacOS using CMake.

A die can house multiple AMD TrueAudio DSP cores, each having 32KiB instruction and data caches and 8KiB of scratchpad memory for local operation.