[3] The foundation was established in September 2003[3][4] by Elena Franchuk, the daughter of Leonid Kuchma, the second post-Soviet Ukrainian President.
[5] In 2010, Elena Pinchuk entered the UNAIDS High Level Commission on HIV Prevention.
[6][7] In 2011, the Foundation launched a competition to develop social media and mobile phone projects for HIV prevention.
[8] In October 2022, the Elena Pinchuk Foundation, together with the NGO Hryhoriy Skovoroda Institute for Process Oriented Work in Ukraine, announced the launch of the Regeneration project to train specialists to provide psychological support to war-affected Ukrainian women.
[9] On October 18, 2010, Victor and Elena Pinchuk received the "Enduring Vision" award from Elton John AIDS Foundation for their contribution to the fight against HIV/AIDS.