ARA Santa Cruz was an auxiliary ship of the Argentine Navy, built in the Fairfield Shipbuilding & Engineering Shipyard, Govan, Scotland, in 1921.

This ship featured a metal hull and superstructure, which included two masts and a single funnel, a characteristic design for tankers during that period.

[3] The tanker Santa Cruz was ordered by the Argentine Naval Commission in London by direct contract with Fairfield Shipbuilding and Engineering Company shipyard, signed in November 1920; the cost was £345,000 STG.

[1] Santa Cruz was launched on 22 June 1921, completed in November, and arrived in Buenos Aires on 28 December 1921 with an Argentine Navy crew led by Frigate Captain Pedro Casal.

[1] On 13 October 1942 her crew rescued survivors from the American Liberty ship John Carter Rose sunk by the German submarine U-201 about 620 nmi (1,150 km; 710 mi) east of Trinidad.