11273233871ENSG00000168488ENSMUSG00000032637Q8WWM7Q7TQH0NM_148415NM_148416NM_183020NM_001347658NM_001361487NP_680781NP_680782NP_001334587NP_898841NP_001348416Ataxin-2-like protein was initially identified in 1996 and designated Ataxin-2 Related protein (A2RP) as the search for the gene causing SCA2 lead to the identification of 2 cDNA clones with high similarity to ATXN2 (Pulst et al, 1996).
[5][6][7] This gene encodes an ataxin type 2 related protein of unknown function.
This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders.
Several alternatively spliced transcripts encoding different isoforms have been found for this gene.
[7] ATXN2L has been shown to interact with Myeloproliferative leukemia virus oncogene.