A Change of Skin (Spanish: Cambio de piel) is a 1967 novel written by Carlos Fuentes about a Mexican writer and his Jewish American wife.

This is the story about a frustrated Mexican writer named Javier, and his Jewish American wife, Elizabeth.

A man named Franz (a Czechoslovakian who helped construct the Nazi concentration camp, Theresienstadt and thereafter fled to Mexico) is with them, along with his young Mexican mistress, Isabel.

Once the two couples have left Mexico, they visit the pre-Columbian ruins at Xochicalco and then the pyramids at Cholula.

There they are joined by the ubiquitous Narrator, who is also en route to Cholula, just to complicate matters even more.