In the episode, Professor Farnsworth leaves Earth after being frustrated by anti-evolutionists' belief in "Creaturism", a form of Creationism.
The nanobots rapidly begin evolving into mechanical organisms, allowing the crew to witness a whole new evolutionary history that unfolds before their eyes.
The episode was written by Dan Vebber and directed by Dwayne Carey-Hill and received mostly mixed reviews from critics.
A fed up Farnsworth resolves to leave Earth and takes the rest of the crew with him to an abandoned planet to live in solitude.
Bender represents him in court and in his arguments, states that Farnsworth is not arguing against evolution, but only claims a small role in beginning it by providing the materials necessary (i.e., the nanobots).
It could also be considered a reference to William Paley's Watchmaker analogy, a teleological argument found in his work Natural Theology.
The episode includes several cultural references related to depictions of evolutionary history and the debate between evolution and creationism.
The crew's encounters with the robotic dinosaurs and Amy's two-piece cavewoman outfit are parodies of the 1940 fantasy film, One Million B.C.