[12] Initial voice actor contract talks resulted in a dispute, with 20th Century Fox reportedly refusing to meet the cast's demands for $75,000 per episode.

[17] Groening, Cohen and the cast expressed extreme optimism for the return of Futurama, with Katey Sagal and Phil LaMarr claiming that the new season's episodes are "hysterical" and "the best yet".

[12][19] "Overclockwise" was originally written to serve as an open-ended series finale, much in the way that the season 4 episode "The Devil's Hands Are Idle Playthings" and the film Into the Wild Green Yonder were produced, in case the show did not get renewed.

[23] A rogue death sphere called the V-GINY, bent on censoring and destroying planets it deems to be indecent, is headed for Earth.

The V-GINY arrives at Earth and decides to spare it if "Adam" (Zapp) and "Eve" (Leela) have sexual intercourse, which they do much to the horror of the Planet Express crew.

Everyone in New New York buys the latest, state of the art eyePhone, a device developed by Mom which is implanted in a person's eye that allows users to record videos and post them online.

Fry and Bender challenge each other to see who can gain one million followers on their Twitcher accounts, with the loser having to dive into a pool of goat vomit and diarrhea.

With Bender in the lead, Fry resorts to posting an embarrassing video of Leela revealing she has a singing boil on her rear named Susan, gaining him enough followers to end the bet with a tie.

He moves into the Planet Express building and decides to take up dating again, falling in love with a female Omnicronian named Grrl until he discovers her to be a human in a costume who saw him at Comic Con.

After making their 100th delivery, for which Bender organizes a huge party, the Planet Express crew is invited to a fund raiser for giving sewer mutants the needed donations to keep them away from the surface.

Seeing how upset Leela is by this, Fry publicly lets slip that she is a mutant living illegally on the surface, causing her to be banished to the sewers for life.

To appease Leela's anger and understand the life of a mutant, Fry jumps into a pool of toxic waste and emerges as a hideous blob.

Bender creates duplicates of himself to get out of doing work, but the clones end up replicating and causing mass intoxication when they reach atomic level and manipulate the water molecules into alcohol.

An episode featuring Futurama animated in three retro styles: "Child Labor Syndicate Presents: Colorama in Glorious Black and White" has Futurama as a black-and-white, rubber-hose cartoon from the 1930s, "Future Challenge 3000" has the show as an early 1980s low-resolution video game, and Action Delivery Force has the show as a 1970s Japanese cartoon.