It is about the eponymous genetically modified mice, who are bent on world domination, attempting to deceive Santa Claus into delivering hypnotic devices as presents during Christmas.

Although released on DVD with season 1 of the series, A Pinky and the Brain Christmas was originally aired December 13, 1995 on The WB as a prime time special.

The mice set off by plane, hiding in a dummy while a female pilot unwittingly flies them to the North Pole, while Pinky continuers to write his list.

The special was produced by Amblin Entertainment and Warner Bros. Television, based on a teleplay by Peter Hastings and directed by Rusty Mills.

A Pinky and the Brain Christmas marked the prime time debut, airing on The WB on the night of Wednesday, December 13, 1995 as a special.

[1] In 2005, authors Kevin Cuddihy and Phillip Metcalfe named it second in their Christmas-themed list of "Not-so-Classic Cartoons", declaring it "well worth the effort to see it".

[8] In 2016, Mary Grace Garis of Bustle wrote that the Emmy win was surprising, crediting it to "Pinky's sweet, simple heart".