The characters eventually returned to their roots as an Animaniacs skit in the 2020 revival of that series.
Outside of both the original Animaniacs and its revival, there were 65 Pinky and the Brain episodes produced.
The episode list reflects the show as aired in repeats and syndication and presented on the series DVDs; some initial Season 1 episodes had two or more programming variations on their first run.
Brain attempts to use a tobacco company to take over the world by selling cigarettes to children.
However, Pinky becomes disgusted at what Brain is trying to do and convinces him to double-cross the tobacco company.