Hill played in Major League Baseball (MLB) for the Toronto Blue Jays, Arizona Diamondbacks, Milwaukee Brewers, Boston Red Sox, and San Francisco Giants.

[2] Hill turned down the offer, opting to attend Louisiana State University and play for the varsity Tigers baseball team.

Hill would finish the game 2-for-4, and he recorded an RBI triple off Nationals pitcher Claudio Vargas for his first career hit as the Blue Jays won, 6–1.

After the trade of Orlando Hudson to the Arizona Diamondbacks, Hill became the starting second baseman for the Blue Jays in 2006, but was moved back to shortstop mid-season after the demotion of Russ Adams.

On May 29, Hill suffered a Grade II concussion in a collision with teammate David Eckstein during a game against the Oakland Athletics.

[17] Hill hit his first home run as a Diamondback on August 28 against the San Diego Padres, a two-run shot to right field off starter Cory Luebke.

[19] On April 7, 2012, Hill, who got moved up in the order to the #2 spot, went 2-for-4 with 3 RBI and two home runs against the Giants in the first and second innings, both off of Madison Bumgarner.

[22] On January 30, 2016, Hill was traded to the Milwaukee Brewers along with Chase Anderson, Isan Diaz, and cash considerations for Jean Segura and Tyler Wagner.

[24] On July 7, 2016, the Brewers traded Hill to the Boston Red Sox for Aaron Wilkerson and Wendell Rijo.

[26] Through 80 plate appearances, Hill managed just a .132 batting average with a home run, 7 RBI, and a strikeout to walk ratio of 13/11.