Abai Region (Kazakh: Абай облысы, romanized: Abai oblysy, pronounced [ɑˈbɑj wobləˈsə]) is a region of Kazakhstan.

President Kassym-Jomart Tokayev announced on 16 March 2022 that the region would be created.

The area split off from East Kazakhstan Region when Tokayev's bill came into force on 8 June 2022.

The administrative center of the region is Semey, until 2007 known as Semipalatinsk.

[4] The city of Semey is the administrative center of the region of Abai.