[2] He was closely connected to King Abdullah the First, and one of the leaders of the Palestinian Arab Communist Party.Al-Karmi was born in Tulkarm in the West Bank in 1906.

[1] He completed his secondary education with his younger brother, Abdul Karim al-Karmi, at the Anbar Office School in Damascus.

[3] Al-Karmi completed his university education in the Soviet Union;[4] He was among the first members of the Palestine Communist Party who studied on scholarships in Moscow in the late 1920s.

He completed his secondary education in Salt (Trans-Jordan) and then in Maktab Anbar in Damascus, where he obtained the Syrian baccalaureate in 1927.

Al-Karmi connected with other Arab figures, including Amjad Al-Trabelsi, Ezz Al-Din Al-Qassam, Saeed Al-Afghani, Ali Al-Tantawi, Anwar Al-Attar [ar], Dhaf Al-Qasimi, and Mutlaq Abdul-Khaleq.

[9] Al-Karmi participated in the founding of the National Liberation League in Palestine, affiliated with the Palestinian Communist Party from 1943 to 1944.