[2] He was born in Tulkram in Palestine for well-known family, his father is Saeed Alkarmi, his brothers are, Abdulkareem, Hassan, Abd al-Ghani and Ahmad Shakir.

He worked in Arabic language field in Egypt and Eritrea, Somalia, Syria, Palestine, Lebanon and Jordan for many years.

Mahmoud Saeed Ali Mansoor AlKarmi was born in 1889 in Tulkram city in Palestine and grew up there in well-known family in literature.

He got education in Tulkram, then he went to Al Azhar with his brother Ahmed Shaker Alkarmi,[3] where he Graduated in 1919 in Arabic language.

[citation needed] In the beginning of his career, Mahmood Alkarmi worked as a teacher in Egypt's schools like Faculty of Dar al-Ulum in Cairo, also as language editor for theatrical novels like plays and novels of the Egyptian playwright Salaama Hijaazi.

It was interested in literature and politics until it was suspended by government for criticizing the imposed British Treaty project on Jordan and Palestine.

His political opponents assassinated him on 24 December 1939/13 Dhu al-Qi'dah 1358 in Beirut, where he was assassinated at the direct instruction of Amin al-Husseini by shooting him with a gun the moment he entered his residence at night,[19] and his body was transported to Tulkarm for burial in an official and popular funeral, and a large memorial ceremony was held for him in the city, delegations from all regions participated in it, during which speeches were delivered by Hashem Jayyusi, Sulaiman Touqan, Hikmat al-Masry and others.