He graduated from the Tashkent Police School (now the Academy of the Ministry of Internal Affairs of Uzbekistan).

From 1982 to 2001, he served in the Main Department of Internal Affairs of the city of Tashkent from the inspector of the checkpoint to the first deputy chief of the GUVD.

After the death of former President of Uzbekistan Islam Karimov and Shavkat Mirziyoyev coming to power in his place, on 4 January 2017, Azizov was appointed Minister of Internal Affairs instead of Adham Ahmedbaev.

10 days after being appointed Minister of the Interior, he was awarded the title of Major General.

On 11 February he was relieved of his post of Minister of Defense and appointed chairman of the State Security Service instead of Ihtiyor Abdullayev.