Syedna Abduttayyeb Zakiuddin II (died on 12 Zil Qa'dah 1110 AH/1692 AD, Jamnagar, India) was the 35th Da'i al-Mutlaq of the Dawoodi Bohras.
Syedna Abduttayeb was 47 when he assumed the office of the Dai in 1676 AD and retained Jamnagar as the center of administration.
He visited Ahmedabad in 1090 AH to launch several religious, economic and social revival programs.
He conferred succession on his son Syedna Musa Kalimuddin in 1091 AH.
Syedna Zakiuddin died at the age of 63 due to ailing health.