A new drift was opened in 1906, giving the combined colliery access to the Eighteen Feet, Four-Feet, Nine-Feet, Three-Feet and Cornish seams.
A £750,000 investment in the early 1970s led to extraction from the Pentreclwylla Fault, but the National Coal Board closed Aberpergwm on 7 October 1985.
In July 2015, after the bankruptcy filing by Walter Energy, the mine ceased production and was placed on a "care and maintenance" basis.
It is to provide integrated healthcare services for Glynneath, Cwmgwrach, Pontneddfechan, Ystradfellte, Rhigos, Resolven, Clyne and Abergarwed.
It will be run by Swansea Bay University Health Board, the Vale of Neath Medical Practice and D R Cecil Jones Pharmacy.