He was born on 12 April 1679 in Aintab and started his religious vocation as a priest in 1706 in the Armenian Apostolic Church.

In 1714, many Armenian converts to Catholicism decided to congregate independently under the leadership of Bishops Melkon Tazbazian and Abraham Ardzivian, with both being in prison.

Tazbazian died in prison and Ardzivian, being liberated briefly was imprisoned again on Rouad Island from 1719 to 1721.

He founded the Kreim convent and St-Antoine's Armenian Catholic Monks order.

Upon his return, to Lebanon, he served as Catholicos-Patriarch aided by 6 clergy and a number of Armenian Catholic monks.