He edited the work Me-Harere Nemerim (Venice, 1599), a collection of several methodological essays and commentaries on various Talmudic treatises.
Akra is the author of a methodological treatise on the Midrash Rabbot, which Isaiah Horowitz (של"ה) embodied in his work Shene Luḥot ha-Berit (ed.
The same thing occurs in the Vilna edition of the Midrash Rabbot, where Akra's treatise is reproduced from the Shene Luḥot ha-Berit.
Akra's work appeared originally as an appendix to the Arze Lebanon, a collection of kabalistic essays, Venice, 1601.
Abraham makes there the interesting statement that he saw in Egypt the manuscript of the Midrash Abkir.