The Academy was designed by the Atlanta architecture firm of Hentz, Adler & Shutze, with R. Kennon Perry the project architect and Philip Trammell Shutze the supervising principal.

Shutze's austerely classical design is reminiscent of the work of John Soane and Benjamin Latrobe.

[3] In 2008, Atlanta Medical Heritage, Inc. donated the Academy of Medicine to the Georgia Tech Foundation, Inc. due to lack of resources to maintain the facility.

The spacious auditorium provides seating for 250, and may be used for ceremonies, seminars, musical performances or lectures.

The building also has a large central rotunda with a domed ceiling from which the chandelier from Gone with the Wind hangs, which host weddings.