guglia, needle) migrated from Brescia to Florence in 1160 because they were Guelphs and fled Barbarossa's invasion of Northern Italy.
The Acciaioli founded a powerful bank in the 13th century (Compagna di Ser Leone degli Acciaioli e de' suoi consorti) which had branches from Greece to Western Europe until the bank collapsed in 1345.
[1] Bishop Angiolo Acciaioli briefly ruled Florence in the mid-14th century after the deposition of Gauthier de Brienne.
From about 1390 to 1460 they ruled the Duchy of Athens and kept close ties with the younger branch of the Medici through the marriage of Laudomia Acciaioli to Pierfrancesco de' Medici, from which the later Grand Dukes of Tuscany are descended, as well as several royal houses.
Simone di Zanobi Acciaioli migrated before 1512 to the island of Madeira where he represented the family's commercial interests.