[2] After Sarah Acland's death her friends decided that an institution for nurses would be an appropriate way to memorialize her, and they solicited donations and collected £4,000 from members of the community.

[3] In 1879 a meeting was held announcing the "Sarah Acland Institution for Nurses", which was initially situated at 37 Wellington Square, Oxford and was supervised by Mrs Rutherford Smith.

[3] The new buildings for the Sarah Acland Home were opened on 12 May 1879 by then-Prince of Wales and later King of the United Kingdom, George V.[4][5] In her 1893 autobiography Recollections of Life and Work, Louisa Twining noted that the facility provided "a most urgent need in the city".

[7] A new wing of the hospital was opened in October 1906 which contained operating rooms and sterilization equipment, and the Queen sent a congratulatory letter to the Regius Professor of Medicine at Oxford, Dr.

[8] Sir Henry Acland retired from his Regius Professorship at Oxford in 1894, and he apportioned a large percentage of a £3,000 testimonial to the Home for Nurses for expansion.

[24] Part of the old hospital, now called Sarah Acland House, is a Grade II listed building, and a challenge in construction was preserving this structure.

The second extension by Robert Langton Cole was built between 1905 and 1906, and opened on 13 October 1906, the bulk of the funds having been raised by Sarah Angelina Acland.

[26][27] In his 1899 work The Cathedral Church of Oxford, Percy Dearmer described the building as a "medallion in statuary marble, set in giallo antico".