To date, the AR spectrometer has successfully differentiated and quantified sample analytes in various forms; (tablets, powders, and liquids).
It has been used to measure and monitor the progression of chemical reactions, such as the setting and hardening of concrete from cement paste to solid.
From a comparison of theoretical attenuation to experimental observation, the particle size distribution and aggregation phenomena are inferred.
[1] Most published work in acoustics has been in the ultrasonic region and their instrumentation has dealt with propagation through a medium and not a resonance effect.
The researchers designed a V-shaped quartz rod instrument that utilized ultrasonic waves to obtain signatures of microliters of different liquids.
Specifically, Sinha was working on developing an ARS instrument that can detect nuclear, chemical, and biological weapons.
In addition, the instrument was further developed by a different research group (Dr. Robert Lodder, University of Kentucky) and their work was also published in Applied Spectroscopy.
White noise is generated and the voltage is converted into a sound wave by a piezoelectric disc[3] coupled to the quartz rod.
Currently, there are no unfailing methods to eliminate contaminated or mislabeled products, a process which sometimes results in millions of pills having to be recalled.
More studies need to be completed to determine if ARS could be used as a process analytical technique in industry to prevent problems with pills before they are shipped.