Acridone alkaloids

[1] Acridone alkaloids are found in bark, wood, leaves and roots of rue plants,[1] especially in roots and suspension cultures of rue.

Further members are acronycin, melicopicine and rutacridone, among others:[1][3] Many acridone alkaloids are methylated on the nitrogen atom and also have two oxygen functional groups, which can be free, alkylated or incorporated into rings.

Acridone alkaloids show a blue-green fluorescence so that they can be detected with UV light.

Some alkaloids of this group are effective against malaria pathogens.

Furthermore, acronycin inhibits cell division.