Acrodonta are a subclade of iguanian squamates consisting almost entirely of Old World taxa.

Extant representation include the families Chamaeleonidae (chameleons) and Agamidae (dragon lizards), with at least over 500 species described.

A fossil genus, Gueragama, was found in Brazil making it the only known American representative of the group.

[1] The group is eponymously named from their acrodont dentition, whereby the teeth are consolidated with the summit of the alveolar ridge of the jaw without sockets.

[4][5] However a majority of papers concerning acrodont phylogenetics support the traditional dichotomy of the group.