Acrophialophora fusispora is a poorly studied ascomycete fungus found in soil, air and various plants.

[2] A. fusispora is morphologically similar to the genera Paecilomyces and Masonia, but differ in the presence of pigmented conidiophores, verticillate phialides, and frequent sympodial proliferation.

[6] Acrophialophora fusispora is similar to Paecilomyces, but differ in the presence of pigmented, warted conidiophores, verticillate phialides in limited numbers with narrowing tip, and frequent sympodial proliferation.

[3] The conidia arises in long single-cell basipetal chains, ranging from colorless to pale-brown and broadly ellipsoidal to lemon-shaped.

[8] The conidiophores arise singly, terminally, and laterally from the hyphae, and are erect or ascending, straight or flexuous, smooth or rough, and septate.

[10] The phialides are flask-shaped and swollen near the base, with a long, narrow neck, and hyaline, smooth or spiny wall.

[3][4] With exception of records from Czechoslovakia, Singapore, Tuamotu Archipelago, Egypt, and Pakistan, A. fusispora is almost exclusively reported from India.

[3] Moreover, in the rhizosphere of Trigonella foenum-graecum, foliar spray with the antibiotic subamycin increases the potential for A. fusispora isolation.